World’s Best Cities in Central America and South America

Our readers had heaps of praise for the best cities in Central and South America, with one word coming up repeatedly: beauty. With their mix of old and new, these places continue to entrance iBestTravel readers.

Every year for our World’s Best Awards survey, iBestTravel asks readers to weigh in on travel experiences around the globe—sharing their opinions on the top cities, islands, cruise ships, spas, airlines, and more. Readers rated cities based on their sights and landmarks, culture, cuisine, friendliness, shopping, and overall value.

1. Cuzco, Peru

Score: 85.66

Location, location, location. Cuzco is perennially popular, in part because it’s the nearest large city to Machu Picchu, one of the world’s most popular travel destinations. However, this ancient town has much to offer in its own right. “We visited on our honeymoon,” wrote one reader. “The local food was hearty, healthy, and delicious, and we were impressed with everything we tried there. We still crave all of it!” Another voter highlighted the “interesting history and old Spanish-style buildings.” Yet, it was the small moments that mattered most for one voter, who “loved getting to take a picture with the locals and hold a baby llama.”

2. Antigua Guatemala, Guatemala

Score: 83.26

3. Buenos Aires, Argentina

WBA Hall of Fame honoree. Score: 82.92

4. Mendoza, Argentina

Score: 82.53

5. Quito, Ecuador

Score: 82.22

6. Rio de Janeiro, Brazil

Score: 81.38

7. Cartagena, Colombia

Score: 81.01

8. Bogotá, Colombia

Score: 79.37

9. Lima, Peru

Score: 78.92

10. Valparaiso, Chile

Score: 78.25

Each city on this prestigious list showcases its unique charm and allure, drawing in travelers from around the globe. Readers have noted vibrant cultures, stunning sights, and unforgettable culinary experiences across these top-rated cities in Central and South America.