Top Road Trips in Argentina with iBestTravel

Argentina’s distinctive reputation looms large in imaginations oceans away from its borders. There’s so much to take in, and such immense distances to travel to do so.

Flights may zoom over remarkable landscapes, while bus travel often leaves much to be desired. Thus, the best option is to explore the country with your own vehicle, granting you the freedom to branch off and pull over whenever you wish.

These road trips showcase a diverse array of breathtaking landscapes and cultural icons—from suave cities and mesmerizing deserts to Andean peaks and charming wine country haunts. Prepare for an epic journey with ample drinks, food, and fuel, as the distances between settlements can be vast.

1. The Pan-American Highway

Best long-distance road trip
From Christ the Redeemer Tunnel to Ushuaia; 4353km (2704 miles); allow 2–4 weeks

Starting the final Argentine leg of its cross-continental adventure at the Christ the Redeemer tunnel, the Pan-American Highway ranks as the world’s most epic road trip. Spanning over 30,000 kilometers (18,640 miles) from Northern Alaska down to Ushuaia in Tierra del Fuego, this route offers breathtaking scenery at every turn.

This southernmost section crosses through Mendoza province, the heart of Argentina’s wine industry, before sweeping down Ruta 3 into the sparsely populated expanse of Patagonia. Notable stops include Puerto Madryn, famous for whale watching, and culminates in Ushuaia, often heralded as “El Fin del Mundo” (The End of the World)—a prime launching point for Antarctic excursions.

Planning tip: The best time for this journey is between September and February, when the weather is mild, and make sure your rental agreement covers entry into Chile, if desired.

2. Camino del Che

Best route for revolutionaries and history lovers
From Buenos Aires to Bariloche; 2438km (1514 miles); allow 1–2 weeks

Ernesto “Che” Guevara spent a significant part of his life in Argentina, and the Camino del Che invites you to explore important locations associated with his upbringing. Starting in Buenos Aires, follow the path northwest along the Río Paraná, eventually reaching Córdoba, home to stunning colonial architecture.

As you travel, explore the fishing town of Cafayate, renowned for its Torrontés wine, and conclude your journey along the picturesque Ruta de Siete Lagos, which offers beautiful lakes and magnificent views of Patagonia’s natural wonders.

3. Ruta del Vino

Best for wine lovers
From Salta to Mendoza; 2022km (1256 miles); allow 1–2 weeks

Argentina ranks as a powerhouse in the South American wine industry, particularly known for its rich Malbec varietals. Your journey along the Ruta del Vino unfolds through fertile valleys, stunning mountains, and charming towns offering ample opportunities to sample local wines.

Beginning in the tranquil city of Salta, venture through breathtaking landscapes to Cafayate, home to aromatic white wines. Continue onward to Mendoza, known as the world capital of Malbec—where you can indulge in vineyard tours, tastings, and even wine spas.

Planning tip: March to May, during Argentina’s autumn, is an optimal time for this journey, coinciding with the grape harvest.

4. Ruta 40

Best route for epic adventure
From El Calafate to Bariloche; 1626km (1010 miles); allow 1–2 weeks

The legendary Ruta 40 (La Cuarenta) holds a special place in the hearts of Argentines, comparable to the famous Route 66 in the USA. Spanning from the Strait of Magellan to the Bolivian border, this road trip features stunning vistas and remarkable landmarks.

Your journey begins in El Calafate, known for its accessible glaciers, winding past mesmerizing lakes and mountain ranges before reaching the picturesque Bariloche, nestled beside Lago Nahuel Huapi.

Planning tip: This trip is ideal for experienced drivers during spring or summer, as Ruta 40 is predominantly paved. A 4WD vehicle is recommended for exploring side roads.

5. Ruta 25

Best route for Welsh culture and whales
From Esquel to Puerto Madryn; 757km (470 miles); allow 5–7 days

Esquel, situated on the Old Patagonian Express route, is a hiking hub surrounded by the stunning Parque Nacional Los Alerces. This area remains influenced by 19th-century Welsh immigrants, and you can experience genuine local culture in towns like Trevelin, where Welsh traditions persist.

The drive traverses arid expanses, eventually leading you to Puerto Madryn, renowned for its whale watching ventures in the nearby Peninsula Valdés. Here, you might encounter orcas and southern right whales in their natural habitat.

This insightful compilation aims to inspire your next road adventure across Argentina’s breathtaking landscapes. Choose a route that resonates with your sense of adventure and prepare for a memorable journey with iBestTravel.